Listen as Dr. Carolyn Dean speaks about MTHRF, methylation, candida and ReAline in this final LIVE broadcase for 2014. Comments are based in part by Ben Lynch’s recent article: Methylation Inhibited by Candida’s Toxin
Lynch talks about the Methionine Pathway and the Methionine Synthase doesn’t work if you
1) lack the active substrate such as methylfolate (Vit-B9)
2) lack cofactors such as methylcobalamin (Vit-B12), and
3) are exposed to inhibiting compounds such as heavy metals, solvents, chemicals, and toxins like acetylaldehyde
Candida produces Acetylaldehyde! Acetylaldehyde is a byproduct of alcohol. It’s call the hangover chemical.
Four key routes of AH arrival are:
- Alcohol consumption
- Candida Albicans (the “Yeast syndrome”) – which produces alcohol…
- Exhaust from cars and trucks
- Cigarette smoking
They all stress the body and use up magnesium. Aldehyde Dehydrogenase breaks down acetylaldehyde but needs magnesium to do that. Besides magnesium and minerals, Carolyn has a secondary focus: yeast overgrowth. Antibiotics, Birth Control Pills, Cortisone, as well as “Stress!” (which actually causes increased production of Cortisone… excessive sugar and carb consumption (especially Hi Fructose Corn Syrup which turns into ethanol) lead to Yeast overgrowth, which then causes an increase in AH in the gut.
To Repeat: Acetylaldehyde kills methionine synthase disrupting the Methylation and Sulfation Pathways. But in my humble opinion…this dysfunction is NOT due to a “gene mutation!” it is very much Epigenetic (as I’ve always suspected…) due to excess “Stressors!” and the lack of proper minerals, especially my favorite, Magnesium, prevents the proper breakdown of this neurotoxin, Acetylaldehyde… Note: the “Stress!” of AH causes the metabolic dysfunction.
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